Prof. Jez received his B.S. in biochemistry from Penn State University (1992), a Ph.D. in biochemistry & molecular biophysics from the University of Pennsylvania (1998), and was an NIH-NRSA postdoctoral fellow at the Salk Institute (1998-2001). After working as a scientist at Kosan Biosciences, he started his research group at the Donald Danforth Plant Science Center in 2002 and moved to the Department of Biology at Washington University in 2008. In 2014, he was selected as a Howard Hughes Medical Institute Professor. Research in the Jez lab seeks to understand how environmental changes re-model biochemical pathways in plants at the molecular, cellular, and organism levels with the aim of engineering these systems to address agricultural and environmental problems. A long-standing research interest is how proteins in a variety of pathways linked to sulfur metabolism function; this work uses a combination of structural biology, protein chemistry, and plant biology.